Title Mathematical Modelling of the Cell Cycle Stress Response Author(s) Radmaneshfar, Elahe Publication Cham, Springer International Publishing, 2014. Description XV, 109 p. 36 illus., 29 illus. in color : online resource Abstract Note The cell cycle is a sequence of biochemical events that are controlled by complex but robust molecular machinery. This enables cells to achieve accurate self-reproduction under a broad range of conditions. Environmental changes are transmitted by molecular signaling networks, which coordinate their actions with the cell cycle. ?? This??work presents the first description of??two complementary computational models??describing the influence of osmotic stress on the entire cell cycle of S. cerevisiae. Our models condense a vast amount of experimental evidence on the interaction of the cell cycle network components with the osmotic stress pathway. Importantly, it is only by considering the entire cell cycle that we are able to make a series of novel predictions which emerge from the coupling between the molecular components of different cell cycle phases. ?? The model-based predictions are supported by experiments in S. cerevisiae and, moreover, have recently been observed in other eukaryotes. Furthermore our models reveal the mechanisms that emerge as a result of the interaction between the cell cycle and stress response networks ISBN,Price 9783319007441 Keyword(s) 1. Applications of Graph Theory and Complex Networks 2. BIOINFORMATICS 3. Biological and Medical Physics, Biophysics 4. BIOLOGICAL PHYSICS 5. BIOMATHEMATICS 6. BIOPHYSICS 7. Cell cycle 8. Cell Cycle Analysis 9. Computational Biology/Bioinformatics 10. EBOOK 11. EBOOK - SPRINGER 12. PHYSICS 13. Physiological, Cellular and Medical Topics Item Type eBook Multi-Media Links Please Click here for eBook Circulation Data Accession#   Call# Status Issued To Return Due On Physical Location I05872     On Shelf