TitleSurface-Enhanced Raman Spectroscopy : Bioanalytical, Biomolecular and Medical Applications
Author(s)Prochazka, Marek
PublicationCham, Springer International Publishing, 2016.
DescriptionXVI, 221 p. 78 illus., 27 illus. in color : online resource
Abstract NoteThis book gives an overview of recent developments in RS and SERS for sensing and biosensing considering also limitations, possibilities and prospects of this technique. Raman scattering (RS) is a widely used vibrational technique providing highly specific molecular spectral patterns. A severe limitation for the application of this spectroscopic technique lies in the low cross section of RS. Surface-enhanced Raman scattering (SERS) spectroscopy overcomes this problem by 6-11 orders of magnitude enhancement compared with the standard RS for molecules in the close vicinity of certain rough metal surfaces. Thus, SERS combines molecular fingerprint specificity with potential single-molecule sensitivity. Due to the recent development of new SERS-active substrates, labeling and derivatization chemistry as well as new instrumentations, SERS became a very promising tool for many varied applications, including bioanalytical studies and sensing. Both intrinsic and extrinsic SERS biosensing schemes have been employed to detect and identify small molecules, nucleic acids and proteins, and also for cellular and in vivo sensing
ISBN,Price9783319239927
Keyword(s)1. Biological and Medical Physics, Biophysics 2. BIOLOGICAL PHYSICS 3. Biological Techniques 4. Biology???Technique 5. BIOPHYSICS 6. EBOOK 7. EBOOK - SPRINGER 8. Measurement Science and Instrumentation 9. Measurement?????? 10. Medical and Radiation Physics 11. Medical physics 12. MICROSCOPY 13. PHYSICAL MEASUREMENTS 14. RADIATION 15. SPECTROSCOPY 16. Spectroscopy and Microscopy
Item TypeeBook
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