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Title | Dual-Mode Electro-photonic Silicon Biosensors |
Author(s) | Juan Col??s, Jos?? |
Publication | Cham, Springer International Publishing, 2017. |
Description | XV, 149 p. 105 illus., 89 illus. in color : online resource |
Abstract Note | This highly interdisciplinary thesis reports ontwo innovative photonic biosensors that combine multiple simultaneous measurements to provide unique insights into the activity and structure of surface immobilized biological molecules. In addition, it presents a new silicon photonic biosensor that exploits two cascaded resonant sensors to provide two independent measurements of a biological layer immobilized on the surface. By combining these two measurements, it is possible to unambiguously quantify the density and thickness of the molecular layer; here, the approach???s ability to study molecular conformation and conformational changes in real timeis demonstrated. The electrophotonic biosensor integrates silicon photonics with electrochemistry into a single technology. This multi-modal biosensor provides a number of unique capabilities that extend the functionality of conventional silicon photonics. For example, by combining the complementary information revealed by simultaneous electrochemical and photonic measurements, it is possible to provide unique insights into on-surface electrochemical processes. Furthermore, the ability to create electrochemical reactions directly on the silicon surface provides a novel approach for engineering the chemical functionality of the photonic sensors. The electrophotonic biosensor thus represents a critical advance towards the development of very high-density photonic sensor arrays for multiplexed diagnostics |
ISBN,Price | 9783319605012 |
Keyword(s) | 1. Biological and Medical Physics, Biophysics
2. BIOLOGICAL PHYSICS
3. BIOPHYSICS
4. EBOOK
5. EBOOK - SPRINGER
6. Electrochemistry
7. Electronic materials
8. Interfaces (Physical sciences)
9. Measurement Science and Instrumentation
10. Measurement??????
11. Optical and Electronic Materials
12. OPTICAL MATERIALS
13. PHYSICAL MEASUREMENTS
14. Surface and Interface Science, Thin Films
15. Surfaces (Physics)
16. THIN FILMS
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Item Type | eBook |
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Circulation Data
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Call# | Status | Issued To | Return Due On | Physical Location |
I10390 |
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