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 #  AuthorTitleAccn#YearItem Type Claims
1 Marc Thiriet Intracellular signaling mediators in the circulatory and ventilatory systems I02031 2013 eBook  
2 Eugene V. Koonin Power laws, scale-free networks and genome biology I00422 2006 eBook  
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TitleIntracellular signaling mediators in the circulatory and ventilatory systems
Author(s)Marc Thiriet
PublicationNew York, Springer, 2013.
Description1 online resource
Abstract NoteThe volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to phenomenological models of nano- and microscopic events in a corrector scheme of regulated mechanisms when the vessel lumen caliber varies markedly. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volume 4 is devoted to major sets of intracellular mediators that transmit signals upon stimulation of cell-surface receptors. Activation of signaling effectors triggers the release of substances stored in cellular organelles and/or gene transcription and protein synthesis. Complex stages of cell signaling can be studied using proper mathematical models, once the role of each component is carefully handled. Volume 4 also reviews various categories of cytosolic and/or nuclear mediators and illustrates some major signal transduction pathways, such as NFkappaB axis, oxygen sensing, and mechanotransduction.Reviews signaling pathways in the regulation of circulatory and respiratory function Describes ion and molecular carriers and receptors Integrates biology, chemistry, and physics for a multidisciplinary understanding of physiological flows
NotesIncludes bibliographical references and index
Keyword(s)1. Biological models 2. Cellular signal transduction 3. EBOOK 4. EBOOK - SPRINGER 5. SCIENCE / Life Sciences / Anatomy & Physiology
Item TypeeBook
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Circulation Data
Accession#  Call#StatusIssued ToReturn Due On Physical Location
I02031     On Shelf    

2.    
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TitlePower laws, scale-free networks and genome biology
Author(s)Eugene V. Koonin;Yuri I. Wolf;Georgy P. Karev
PublicationGeorgetown, 1. Landes Bioscience/Eurekah.com 2. Springer Science+Business Media, 2006.
Description1 online resource (257 p.) : ill
Abstract NoteDeals with crucial aspects of the theoretical foundations of systems biology, namely power law distributions and scale-free networks. This book not only describes the interesting mathematical properties of biological networks, but moves beyond phenomenology, towards models of evolution capable of explaining the emergence of these features
Contents NotePower laws in biological networks / Eivind Almaas and Albert-L�aszl�o Barab�asi -- Graphical analysis of biocomplex networks and transport phenomena / Kwang-Il Goh, Byungnam Kahng and Doochul Kim -- Large-scale topological properties of molecular networks / Sergei Maslov and Kim Sneppen -- The connectivity of large genetic networks: design, history, or mere chemistry? / Andreas Wagner -- The drosophila protein interaction network may be neither power-law nor scale-free / J.S. Bader -- Birth and death models of genome evolution / Georgy P. Karev, Yuri I. Wolf and Eugene V. Koonin -- Scale-free evolution: from proteins to organisms / Nikolay V. Dokholyan and Eugene I. Shakhnovich -- Gene regulatory networks / T. Gregory Dewey and David J. Galas -- Power law correlations in DNA sequences / Sergey V. Buldyrev -- Analytical evolutionary model for protein fold occurrence in genomes, accounting for the effects of gene duplication, deletion, acquisition and selective pressure / Michael Kamal ... [et al.] -- The protein universes: some informatic issues in protein classification / S. Rackovsky -- The role of computation in complex regulatory networks / Pau Fern�andez and Ricard V. Sol�e -- Neutrality and selection in the evolution of gene families / Itai Yanai -- Scaling laws in the functional content of genomes: fundamental constants of evolution? / Erik van Nimwegen
NotesIncludes bibliographical references and index
Keyword(s)1. ALGORITHMS 2. Biological models 3. Computational biology 4. EBOOK 5. EBOOK - SPRINGER 6. Genomics 7. Models, Biological 8. SCIENCE
Item TypeeBook
Multi-Media Links
Please Click Here for the Online Book
Circulation Data
Accession#  Call#StatusIssued ToReturn Due On Physical Location
I00422     On Shelf    

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