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 #  AuthorTitleAccn#YearItem Type Claims
1 Solov???yov, Andrey V Nanoscale Insights into Ion-Beam Cancer Therapy I10243 2017 eBook  
2 Scherer, Kai Hermann Grating-Based X-Ray Phase-Contrast Mammography I10182 2016 eBook  
3 Ashcroft, Peter The Statistical Physics of Fixation and Equilibration in Individual-Based Models I09637 2016 eBook  
4 Brombal, Luca X-Ray Phase-Contrast Tomography I09527 2020 eBook  
5 Waterhouse, Dale Jonathan Novel Optical Endoscopes for Early Cancer Diagnosis and Therapy I09304 2019 eBook  
6 La Porta, Caterina AM Understanding Innovation Through Exaptation I08919 2020 eBook  
7 Keidar, Michael Plasma Cancer Therapy I08620 2020 eBook  
8 Almond, Peter R Cobalt Blues I07702 2013 eBook  
9 Linz, Ute Ion Beam Therapy I07133 2012 eBook  
10 Goitein, Michael Radiation Oncology: A Physicist's-Eye View I06834 2008 eBook  
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TitleNanoscale Insights into Ion-Beam Cancer Therapy
Author(s)Solov???yov, Andrey V
PublicationCham, 1. Imprint: Springer 2. Springer International Publishing, 2017.
DescriptionXX, 498 p. 183 illus., 159 illus. in color : online resource
Abstract NoteThis book provides a unique and comprehensive overview of state-of-the-art understanding of the molecular and nano-scale processes that play significant roles in ion-beam cancer therapy. It covers experimental design and methodology, and reviews the theoretical understanding of the processes involved. It offers the reader an opportunity to learn from a coherent approach about the physics, chemistry and biology relevant to ion-beam cancer therapy, a growing field of important medical application worldwide. The book describes phenomena occurring on different time and energy scales relevant to the radiation damage of biological targets and ion-beam cancer therapy from the molecular (nano) scale up to the macroscopic level. It illustrates how ion-beam therapy offers the possibility of excellent dose localization for treatment of malignant tumours, minimizing radiation damage in normal tissue whilst maximizing cell-killing within the tumour, offering a significant development in cancer therapy. The full potential of such therapy can only be realized by better understanding the physical, chemical and biological mechanisms, on a range of time and space scales that lead to cell death under ion irradiation. This book describes how, using a multiscale approach, experimental and theoretical expertise available can lead to greater insight at the nanoscopic and molecular level into radiation damage of biological targets induced by ion impact. The book is intended for advanced students and specialists in the areas of physics, chemistry, biology and medicine related to ion-beam therapy, radiation protection, biophysics, radiation nanophysics and chemistry, atomic and molecular physics, condensed matter physics, and the physics of interaction of charged particles with matter. One of the most important features of the book is the inclusive multiscale approach to the understanding of complex and highly interdisciplinary processes behind ion-beam cancer therapy, which stretches from the atomistic level up to the biological scale and is demonstrated to be in excellent agreement with experimental observations
ISBN,Price9783319430300
Keyword(s)1. Biological and Medical Physics, Biophysics 2. BIOLOGICAL PHYSICS 3. BIOPHYSICS 4. Cancer Research 5. EBOOK 6. EBOOK - SPRINGER 7. Heavy ions 8. Medical and Radiation Physics 9. Medical physics 10. Nanochemistry 11. Nanoscale science 12. Nanoscale Science and Technology 13. NANOSCIENCE 14. Nanostructures 15. NUCLEAR PHYSICS 16. Nuclear Physics, Heavy Ions, Hadrons 17. RADIATION
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TitleGrating-Based X-Ray Phase-Contrast Mammography
Author(s)Scherer, Kai Hermann
PublicationCham, 1. Imprint: Springer 2. Springer International Publishing, 2016.
DescriptionXX, 140 p. 47 illus., 33 illus. in color : online resource
Abstract NoteThis thesis offers an accessible guide to biomedical phase-contrast imaging with over 20 radiographic illustrations. It focuses on research to improve radiography, and particularly mammography applications, by using a novel X-ray imaging modality that exploits the wave-nature of X-rays, rather than just their absorption in tissue. Further, it explores a broad range of potential applications ??? from the assessment of breast cancer and the evaluation of microcalcification clusters, to the examination of renal stones. X-ray imaging is an indispensable tool in modern medical diagnostics, and ranges from simple radiography applications to advanced CT imaging protocols. This novel phase-contrast approach has the potential to deliver significantly improved diagnostic information, also and especially in cases where mammography is used for screening purposes. The thesis is based on several studies conducted by the author ??? working in close interdisciplinary cooperation with medical doctors at two university clinics in Munich ??? and successfully demonstrates this diagnostic potential in pre-clinical experiments
ISBN,Price9783319395371
Keyword(s)1. Cancer Research 2. Diagnostic Radiology 3. EBOOK 4. EBOOK - SPRINGER 5. Medical and Radiation Physics 6. Medical physics 7. RADIATION 8. Radiology
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TitleThe Statistical Physics of Fixation and Equilibration in Individual-Based Models
Author(s)Ashcroft, Peter
PublicationCham, 1. Imprint: Springer 2. Springer International Publishing, 2016.
DescriptionXV, 164 p. 63 illus., 13 illus. in color : online resource
Abstract NoteThis thesis explores several interdisciplinary topics at the border of theoretical physics and biology, presenting results that demonstrate the power of methods from statistical physics when applied to neighbouring disciplines. From birth-death processes in switching environments to discussions on the meaning of quasi-potential landscapes in high-dimensional spaces, this thesis is a shining example of the efficacy of interdisciplinary research. The fields advanced in this work include game theory, the dynamics of cancer, and invasion of mutants in resident populations, as well as general contributions to the theory of stochastic processes. The background material provides an intuitive introduction to the theory and applications of stochastic population dynamics, and the use of techniques from statistical physics in their analysis. The thesis then builds on these foundations to address problems motivated by biological phenomena
ISBN,Price9783319412139
Keyword(s)1. BIOINFORMATICS 2. BIOMATHEMATICS 3. Cancer Research 4. Data-driven Science, Modeling and Theory Building 5. EBOOK 6. EBOOK - SPRINGER 7. ECONOPHYSICS 8. GAME THEORY 9. Game Theory, Economics, Social and Behav. Sciences 10. Mathematical and Computational Biology 11. PROBABILITIES 12. Probability Theory and Stochastic Processes 13. Sociophysics
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TitleX-Ray Phase-Contrast Tomography : Underlying Physics and Developments for Breast Imaging
Author(s)Brombal, Luca
PublicationCham, 1. Imprint: Springer 2. Springer International Publishing, 2020.
DescriptionXIII, 140 p. 68 illus., 53 illus. in color : online resource
Abstract NoteX-ray imaging is a corner stone of breast cancer diagnosis. By exploiting the phase shift of X-rays rather than their attenuation, phase-contrast tomography has the potential to dramatically increase the visibility of small and low contrast features, thus leading to better diagnosis. This thesis presents research on the first synchrotron-based project developing a clinical phase-contrast breast computed tomography (CT) setup at Elettra, the Italian Syncrotron Radiation Facility. This book includes a comprehensive theoretical background on propagation-based phase-contrast imaging, exploring and extending the most recent image formation models. Along with theory, many practical implementation and optimization issues, ranging from detector-specific processing to setup geometry, are tackled on the basis of a large number of experimental evidences. Most of the modelling results and data analysis have general validity, being a valuable framework for optimization of phase-contrast setups. Results obtained at synchrotron are also compared with "real world" laboratory sources: both a first-of-its-kind comparison with one of the few hospital breast CT systems and a state-of-the-art implementation of monochromatic phase-contrast micro-tomography with a conventional rotating anode source are presented. On a more general level, this work sheds a light on the importance of synchrotron-based clinical programs, which are key to trigger the long-anticipated transition of phase-contrast imaging from synchrotrons to hospitals.
ISBN,Price9783030604332
Keyword(s)1. Atomic, Molecular, Optical and Plasma Physics 2. ATOMS 3. Biological and Medical Physics, Biophysics 4. BIOLOGICAL PHYSICS 5. BIOPHYSICS 6. Cancer Research 7. EBOOK 8. EBOOK - SPRINGER 9. Imaging / Radiology 10. PHYSICS 11. Radiology
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TitleNovel Optical Endoscopes for Early Cancer Diagnosis and Therapy
Author(s)Waterhouse, Dale Jonathan
PublicationCham, 1. Imprint: Springer 2. Springer International Publishing, 2019.
DescriptionXXI, 142 p : online resource
Abstract NoteThis thesis describes the design, development, characterisation and clinical translation of three novel devices for optical endoscopic imaging. Over the past decade, rapid innovation in optics and photonics has led to the availability of low-cost and high-performance optical technologies that can be exploited for biomedical applications, but relatively few have been translated into clinic. The work presented outlines for the first time, a comprehensive analysis of the common barriers and unique challenges associated with the translation of optical imaging techniques. To assist developers streamline translation of optical imaging devices in future, a roadmap to clinical translation is outlined, and key translational characteristics are defined. Guided by these, subsequent development of endoscopic devices resulted in preparation and approval of endoscopes for first in human trials in the oesophagus, for early detection of cancer, and in the brain, for delineation of tumour during surgical resection. The thesis culminates in the presentation of results from the first in human use of a compact multispectral endoscope for imaging endogenous tissue contrast in the oesophagus. With continuation of the work as outlined at the end of this thesis, the novel techniques described have the potential to improve the standard of care in their respective indications
ISBN,Price9783030214814
Keyword(s)1. Cancer Research 2. Diagnostic Radiology 3. EBOOK 4. EBOOK - SPRINGER 5. LASERS 6. Medical and Radiation Physics 7. Medical physics 8. Optics, Lasers, Photonics, Optical Devices 9. PHOTONICS 10. RADIATION 11. Radiology
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TitleUnderstanding Innovation Through Exaptation
Author(s)La Porta, Caterina AM;Zapperi, Stefano;Pilotti, Luciano
PublicationCham, 1. Imprint: Springer 2. Springer International Publishing, 2020.
DescriptionX, 194 p. 50 illus., 40 illus. in color : online resource
Abstract NoteThis book explores the role of exaptation in diverse areas of life, with examples ranging from biology to economics, social sciences and architecture. The concept of exaptation, introduced in evolutionary biology by Gould and Vrba in 1982, describes the possibility that already existing traits can be exploited for new purposes throughout the evolutionary process. Edited by three active scholars in the fields of biology, physics and economics, the book presents an interdisciplinary collection of expert viewpoints illustrating the importance of exaptation for interpreting current reality in various fields of investigation. Using the lenses of exaptation, the contributing authors show how to view the overall macroscopic landscape as comprising many disciplines, all working in unity within a single complex system. This book is the first to discuss exaptation in both hard and soft disciplines and highlights the role of this concept in understanding the birth of innovation by identifying key elements and ideas. It also offers a comprehensive guide to the emerging interdisciplinary field of exaptation, provides didactic explanations of the basic concepts, and avoids excessive jargon and heavy formalism. Its target audience includes graduate students in physics, biology, mathematics, economics, psychology and architecture; it will also appeal to established researchers in the humanities who wish to explore or enter this new science-driven interdisciplinary field
ISBN,Price9783030457846
Keyword(s)1. Biological systems 2. Cancer Research 3. CITY PLANNING 4. COMPLEX SYSTEMS 5. DYNAMICAL SYSTEMS 6. EBOOK 7. EBOOK - SPRINGER 8. Evolutionary Biology 9. STATISTICAL PHYSICS 10. Systems biology 11. Urban planning 12. Urbanism
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TitlePlasma Cancer Therapy
Author(s)Keidar, Michael
PublicationCham, 1. Imprint: Springer 2. Springer International Publishing, 2020.
DescriptionX, 310 p. 144 illus., 121 illus. in color : online resource
Abstract NoteThis book, written by key researchers in the field, provides a comprehensive analysis and overview of the state of the art of plasma-based cancer therapy. Recent progress in atmospheric plasmas has led to non-thermal or cold atmospheric plasma (CAP) devices with ion temperatures close to room temperature. In contrast to many existing anti-cancer approaches, CAP is a selective anti-cancer modality which has demonstrated significant potential in cancer therapy. Written by a global, cross-disciplinary group of leading researchers, this book covers basic theory, generation, diagnostics, and simulation of cold atmospheric plasma, as well as their clinical application in cancer therapy, immunotherapy, and future outlook, giving a complete picture of the field. It is meant for a broad audience, from students to engineers and scientists, who are interested in the emerging world of plasma medical applications. It presents recent advances, primary challenges, and future directions of this exciting, cutting-edge field
ISBN,Price9783030499662
Keyword(s)1. Biomedical engineering 2. Biomedical Engineering and Bioengineering 3. Cancer Research 4. EBOOK 5. EBOOK - SPRINGER 6. ONCOLOGY 7. Oncology???? 8. PLASMA (IONIZED GASES) 9. PLASMA PHYSICS
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8.     
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TitleCobalt Blues : The Story of Leonard Grimmett, the Man Behind the First Cobalt-60 Unit in the United States
Author(s)Almond, Peter R
PublicationNew York, NY, 1. Imprint: Springer 2. Springer New York, 2013.
DescriptionXVIII, 158 p : online resource
Abstract NoteFor the latter half of the 20th century, cobalt-60 units were the mainstay of radiation treatments for cancer. Cobalt Blues describes the development of the first cobalt-60 unit in the United States and the man behind it, Leonard Grimmett. Conceptually conceived before World War II, it only became possible because of the development of nuclear reactors during the war. Although Grimmett conceived of and published his ideas first, the Canadians built the first units because of the capability of their reactor to produce more suitable cobalt-60 sources. This book tells the story of how Grimmett and others came together at the time that the U S Atomic Energy Agency was pushing the use of radioactivity in medicine. Due to his sudden death, very little information about Grimmett was known until recently, when various documents have come to light, allowing the full story to be told
ISBN,Price9781461449249
Keyword(s)1. Cancer Research 2. Diagnostic Radiology 3. EBOOK 4. EBOOK - SPRINGER 5. HISTORY 6. HISTORY OF SCIENCE 7. Medical and Radiation Physics 8. Medical physics 9. RADIATION 10. Radiology
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9.     
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TitleIon Beam Therapy : Fundamentals, Technology, Clinical Applications
Author(s)Linz, Ute
PublicationBerlin, Heidelberg, 1. Imprint: Springer 2. Springer Berlin Heidelberg, 2012.
DescriptionXXXV, 729 p. 234 illus., 185 illus. in color : online resource
Abstract NoteThe book provides a detailed, up-to-date account of the basics, the technology, and the clinical use of ion beams for radiation therapy. Theoretical background, technical components, and patient treatment schemes are delineated by the leading experts that helped to develop this field from a research niche to its current highly sophisticated and powerful clinical treatment level used to the benefit of cancer patients worldwide. Rather than being a side-by-side collection of articles, this book consists of related chapters. It is a common achievement by 76 experts from around the world. Their expertise reflects the diversity of the field with radiation therapy, medical and accelerator physics, radiobiology, computer science, engineering, and health economics. The book addresses a similarly broad audience ranging from professionals that need to know more about this novel treatment modality or consider to enter the field of ion beam therapy as a researcher. However, it is also written for the interested public and for patients who might want to learn about this treatment option
ISBN,Price9783642214141
Keyword(s)1. Biomedical engineering 2. Biomedical Engineering and Bioengineering 3. Cancer Research 4. EBOOK 5. EBOOK - SPRINGER 6. ENERGY 7. Energy, general 8. Medical and Radiation Physics 9. Medical physics 10. Nuclear medicine 11. RADIATION 12. Radiotherapy
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10.    
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TitleRadiation Oncology: A Physicist's-Eye View
Author(s)Goitein, Michael
PublicationNew York, NY, 1. Imprint: Springer 2. Springer New York, 2008.
DescriptionXII, 330 p. 120 illus., 40 illus. in color : online resource
Abstract NoteRadiation Oncology: A Physicist's-Eye View was written for both physicists and medical oncologists with the aim of helping them approach the use of radiation in the treatment of cancer with understanding, confidence, and imagination. The book will let practitioners in one field understand the problems of, and find solutions for, practitioners in the other. It will help them to know "why" certain approaches are fruitful while, at the same time, encouraging them to ask the question "Why not?" in the face of assertions that some proposal of theirs is impractical, unreasonable, or impossible. Unlike a textbook, formal and complete developments of the topics are not among the goals. Instead, the reader will develop a foundation for understanding what the author has found to be matters of importance in radiation oncology during over thirty years of experience. Presentations cover, in largely non-technical language, the principal physical and biological aspects of radiation treatment and address practical clinical considerations in planning and delivering therapy. The importance of the assessment of uncertainties is emphasized. Topics include: an overview of the physics of the interactions of radiation with matter; the definition of the goals and the design of radiation therapy approaches; living with uncertainty; biophysical models of radiation damage; computer-based optimization of treatments; and proton therapy. Formulae and quantitation in general have been avoided in the belief that an understanding of the majority of important medical and biological issues in radiation oncology generally cannot be achieved through mathematical relationships. This unique and highly readable book will be indispensable both to beginners and to those with experience in either medical physics or radiation oncology. The author, who is Professor of Radiation Oncology Emeritus at Harvard Medical School, was an early pioneer in the development of image-based treatment planning and has been responsible for developing and putting into clinical practice such widely used tools as: digitally reconstructed radiographs, dose-volume histograms, and beam???s-eye view and has been a leader in the development of proton beam therapy
ISBN,Price9780387726458
Keyword(s)1. Biological and Medical Physics, Biophysics 2. BIOLOGICAL PHYSICS 3. Biomedical engineering 4. Biomedical Engineering and Bioengineering 5. BIOPHYSICS 6. Cancer Research 7. EBOOK 8. EBOOK - SPRINGER
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