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Author | Title | Accn# | Year | Item Type | Claims |
| 1 |
Karschau, Jens |
Mathematical Modelling of Chromosome Replication and Replicative Stress |
I08011 |
2015 |
eBook |
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| 2 |
Garc??a G??mez-Tejedor, Gustavo |
Radiation Damage in Biomolecular Systems |
I05428 |
2012 |
eBook |
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| Title | Mathematical Modelling of Chromosome Replication and Replicative Stress |
| Author(s) | Karschau, Jens |
| Publication | Cham, Springer International Publishing, 2015. |
| Description | XIII, 76 p. 57 illus., 9 illus. in color : online resource |
| Abstract Note | DNA replication is arguably the most crucial process at work in living cells. It is the mechanism by which organisms pass their genetic information from one generation to the next, and life on Earth would be unthinkable without it. Despite the discovery of DNA structure in the 1950s, the mechanism of its replication remains rather elusive. ?? This work makes important contributions to this line of research. In particular, it addresses two key questions in the area of DNA replication: which evolutionary forces drive the positioning of replication origins in the chromosome; and how is the spatial organization of replication factories achieved inside the nucleus of a cell? ?? A cross-disciplinary approach uniting physics and biology is at the heart of this research. Along with experimental support, statistical physics theory produces optimal origin positions and provides a model for replication fork assembly in yeast. Advances made here can potentially??further our understanding of??disease mechanisms??such as the abnormal replication in cancer |
| ISBN,Price | 9783319088617 |
| Keyword(s) | 1. Biological and Medical Physics, Biophysics
2. BIOLOGICAL PHYSICS
3. BIOPHYSICS
4. COMPLEX SYSTEMS
5. DYNAMICAL SYSTEMS
6. EBOOK
7. EBOOK - SPRINGER
8. Genetic engineering
9. Nucleic Acid Chemistry
10. Nucleic acids
11. Numerical and Computational Physics, Simulation
12. PHYSICS
13. STATISTICAL PHYSICS
14. Statistical Physics and Dynamical Systems
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| Item Type | eBook |
Multi-Media Links
Please Click here for eBook
Circulation Data
| Accession# | |
Call# | Status | Issued To | Return Due On | Physical Location |
| I08011 |
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On Shelf |
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2.
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| Title | Radiation Damage in Biomolecular Systems |
| Author(s) | Garc??a G??mez-Tejedor, Gustavo;Fuss, Martina Christina |
| Publication | Dordrecht, Springer Netherlands, 2012. |
| Description | XIV, 510 p : online resource |
| Abstract Note | Since the discovery of X-rays and radioactivity, ionizing radiations have been widely applied in medicine both for diagnostic and therapeutic purposes. The risks associated with radiation exposure and handling led to the parallel development of the field of radiation protection. Pioneering experiments done by Sanche and co-workers in 2000 showed that low-energy secondary electrons, which are abundantly generated along radiation tracks, are primarily responsible for radiation damage through successive interactions with the molecular constituents of the medium. Apart from ionizing processes, which are usually related to radiation damage, below the ionization level low-energy electrons can induce molecular fragmentation via dissociative processes such as internal excitation and electron attachment. This prompted collaborative projects between different research groups from European countries together with other specialists from Canada,?? the USA and Australia. This book??summarizes the advances achieved by these research groups after more than ten years of studies on radiation damage in biomolecular systems. The book will be of interest to researchers and advanced students in the fields of radiation physics, chemistry and radiation therapy |
| ISBN,Price | 9789400725645 |
| Keyword(s) | 1. Biological and Medical Physics, Biophysics
2. BIOLOGICAL PHYSICS
3. BIOPHYSICS
4. EBOOK
5. EBOOK - SPRINGER
6. Effects of Radiation/Radiation Protection
7. Medical and Radiation Physics
8. Medical physics
9. Nucleic Acid Chemistry
10. Nucleic acids
11. RADIATION
12. Radiation protection
13. Radiation???Safety measures
14. Radiotherapy
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| Item Type | eBook |
Multi-Media Links
Please Click here for eBook
Circulation Data
| Accession# | |
Call# | Status | Issued To | Return Due On | Physical Location |
| I05428 |
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On Shelf |
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