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 #  AuthorTitleAccn#YearItem Type Claims
1 Rostovtseva, Tatiana K Molecular Basis for Mitochondrial Signaling I10256 2017 eBook  
2 Radmaneshfar, Elahe Mathematical Modelling of the Cell Cycle Stress Response I05872 2014 eBook  
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TitleMolecular Basis for Mitochondrial Signaling
Author(s)Rostovtseva, Tatiana K
PublicationCham, Springer International Publishing, 2017.
DescriptionXIV, 386 p. 61 illus., 54 illus. in color : online resource
Abstract NoteThis book covers recent advances in the study of structure, function, and regulation of metabolite, protein and ion translocating channels, and transporters in mitochondria. A wide array of cutting-edge methods are covered, ranging from electrophysiology and cell biology to bioinformatics, as well as structural, systems, and computational biology. At last, the molecular identity of two important channels in the mitochondrial inner membrane, the mitochondrial calcium uniporter and the mitochondrial permeability transition pore have been established. After years of work on the physiology and structure of VDAC channels in the mitochondrial outer membrane, there have been multiple discoveries on VDAC permeation and regulation by cytosolic proteins. Recent breakthroughs in structural studies of the mitochondrial cholesterol translocator reveal a set of novel unexpected features and provide essential clues for defining therapeutic strategies. Molecular Basis for Mitochondrial Signaling covers these and many more recent studies of mitochondria function, their communication with other organelles, and their critical roles in development, aging, and in a plethora of stressful or degenerative events. Authored by leading researchers in the field, this volume will be an indispensable reference resource for graduate students and academics working in related areas of biophysics and cell biology as well as for professionals within industry
ISBN,Price9783319555393
Keyword(s)1. Apoptosis 2. Biological and Medical Physics, Biophysics 3. BIOLOGICAL PHYSICS 4. BIOPHYSICS 5. Cell cycle 6. Cell Cycle Analysis 7. EBOOK 8. EBOOK - SPRINGER
Item TypeeBook
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Accession#  Call#StatusIssued ToReturn Due On Physical Location
I10256     On Shelf    

2.    
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TitleMathematical Modelling of the Cell Cycle Stress Response
Author(s)Radmaneshfar, Elahe
PublicationCham, Springer International Publishing, 2014.
DescriptionXV, 109 p. 36 illus., 29 illus. in color : online resource
Abstract NoteThe cell cycle is a sequence of biochemical events that are controlled by complex but robust molecular machinery. This enables cells to achieve accurate self-reproduction under a broad range of conditions. Environmental changes are transmitted by molecular signaling networks, which coordinate their actions with the cell cycle. ?? This??work presents the first description of??two complementary computational models??describing the influence of osmotic stress on the entire cell cycle of S. cerevisiae. Our models condense a vast amount of experimental evidence on the interaction of the cell cycle network components with the osmotic stress pathway. Importantly, it is only by considering the entire cell cycle that we are able to make a series of novel predictions which emerge from the coupling between the molecular components of different cell cycle phases. ?? The model-based predictions are supported by experiments in S. cerevisiae and, moreover, have recently been observed in other eukaryotes. Furthermore our models reveal the mechanisms that emerge as a result of the interaction between the cell cycle and stress response networks
ISBN,Price9783319007441
Keyword(s)1. Applications of Graph Theory and Complex Networks 2. BIOINFORMATICS 3. Biological and Medical Physics, Biophysics 4. BIOLOGICAL PHYSICS 5. BIOMATHEMATICS 6. BIOPHYSICS 7. Cell cycle 8. Cell Cycle Analysis 9. Computational Biology/Bioinformatics 10. EBOOK 11. EBOOK - SPRINGER 12. PHYSICS 13. Physiological, Cellular and Medical Topics
Item TypeeBook
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Please Click here for eBook
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Accession#  Call#StatusIssued ToReturn Due On Physical Location
I05872     On Shelf    

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