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 #  AuthorTitleAccn#YearItem Type Claims
11 Walter, Nils Non-Protein Coding RNAs I07807 2009 eBook  
12 Glaser, Roland Biophysics I07449 2012 eBook  
13 Skulachev, Vladimir P Principles of Bioenergetics I07211 2013 eBook  
14 Beckerman, Martin Cellular Signaling in Health and Disease I06893 2009 eBook  
15 Williams, Mark C Biophysics of DNA-Protein Interactions I06889 2011 eBook  
16 Cicco, Giuseppe Oxygen Transport to Tissue XXVII I06737 2006 eBook  
17 Kurzynski, Michal The Thermodynamic Machinery of Life I06609 2006 eBook  
18 Mateo, C.Reyes Protein-Lipid Interactions I06538 2006 eBook  
19 Martinac, Boris Sensing with Ion Channels I06215 2008 eBook  
20 Holcman, David Stochastic Narrow Escape in Molecular and Cellular Biology I06174 2015 eBook  
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11.    
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TitleNon-Protein Coding RNAs
Author(s)Walter, Nils;Woodson, Sarah A;Batey, Robert T
PublicationBerlin, Heidelberg, 1. Imprint: Springer 2. Springer Berlin Heidelberg, 2009.
DescriptionXI, 398 p : online resource
Abstract NoteThis book assembles chapters from experts in the Biophysics of RNA to provide a broadly accessible snapshot of the current status of this rapidly expanding field. The 2006 Nobel Prize in Physiology or Medicine was awarded to the discoverers of RNA interference, highlighting just one example of a large number of non-protein coding RNAs. Because non-protein coding RNAs outnumber protein coding genes in mammals and other higher eukaryotes, it is now thought that the complexity of organisms is correlated with the fraction of their genome that encodes non-protein coding RNAs. Essential biological processes as diverse as cell differentiation, suppression of infecting viruses and parasitic transposons, higher-level organization of eukaryotic chromosomes, and gene expression itself are found to largely be directed by non-protein coding RNAs. The biophysical study of these RNAs employs X-ray crystallography, NMR, ensemble and single molecule fluorescence spectroscopy, optical tweezers, cryo-electron microscopy, and other quantitative tools. This emerging field has begun to unravel the molecular underpinnings of how RNAs fulfill their multitude of roles in sustaining cellular life. The physical and chemical understanding of RNA biology that results from biophysical studies is critical to our ability to harness RNAs for use in biotechnology and human therapy, a prospect that has recently spawned a multi-billion dollar industry
ISBN,Price9783540708407
Keyword(s)1. BIOCHEMISTRY 2. Biochemistry, general 3. BIOINFORMATICS 4. Biological and Medical Physics, Biophysics 5. BIOLOGICAL PHYSICS 6. BIOPHYSICS 7. CELL BIOLOGY 8. EBOOK 9. EBOOK - SPRINGER 10. Human physiology 11. MOLECULAR BIOLOGY 12. Molecular Medicine
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12.     
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TitleBiophysics : An Introduction
Author(s)Glaser, Roland
PublicationBerlin, Heidelberg, 1. Imprint: Springer 2. Springer Berlin Heidelberg, 2012.
DescriptionXX, 407 p. 188 illus., 134 illus. in color : online resource
Abstract NoteBiophysics is the science of physical principles underlying all processes of life, including the dynamics and kinetics of biological systems. This fully revised 2nd English edition is an introductory text that spans all steps of biological organization, from the molecular, to the organism level, as well as influences of environmental factors. In response to the enormous progress recently made, especially in theoretical and molecular biophysics, the author has updated the text, integrating new results and developments concerning protein folding and dynamics, molecular aspects of membrane assembly and transport, noise-enhanced processes, and photo-biophysics. The advances made in theoretical biology in the last decade call for a fully new conception of the corresponding sections. Thus, the book provides the background needed for fundamental training in biophysics and, in addition, offers a great deal of advanced biophysical knowledge
ISBN,Price9783642252129
Keyword(s)1. BIOCHEMISTRY 2. Biochemistry, general 3. Biological and Medical Physics, Biophysics 4. BIOLOGICAL PHYSICS 5. BIOPHYSICS 6. CELL BIOLOGY 7. EBOOK 8. EBOOK - SPRINGER 9. Effects of Radiation/Radiation Protection 10. Human physiology 11. Radiation protection 12. Radiation???Safety measures
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13.     
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TitlePrinciples of Bioenergetics
Author(s)Skulachev, Vladimir P;Bogachev, Alexander V;Kasparinsky, Felix O
PublicationBerlin, Heidelberg, 1. Imprint: Springer 2. Springer Berlin Heidelberg, 2013.
DescriptionXVI, 436 p : online resource
Abstract NotePrinciples of Bioenergetics summarizes one of the quickly growing branches of modern biochemistry.??Bioenergetics concerns energy transductions occurring in living systems and??this book pays special attention to molecular mechanisms of these processes.??The main subject of the book is the "energy coupling membrane" which refers to??inner membranes of intracellular organelles, for example, mitochondria and chloroplasts. Cellular cytoplasmic membranes where respiratory and photosynthetic energy transducers, as well as ion-transporting ATP-synthases (ATPases)??are also part of this membrane.??Significant attention is paid to the alternative function of mitochondria as generators of reactive oxygen species (ROS) that mediate programmed death of cells (apoptosis and necrosis) and organisms (phenoptosis). The latter process is considered as a key mechanism of aging which may be suppressed by mitochondria-targeted antioxidants
ISBN,Price9783642334306
Keyword(s)1. Biological and Medical Physics, Biophysics 2. BIOLOGICAL PHYSICS 3. BIOPHYSICS 4. CELL BIOLOGY 5. EBOOK 6. EBOOK - SPRINGER 7. Geriatrics 8. Geriatrics/Gerontology 9. Medicinal chemistry 10. PHYSICAL CHEMISTRY
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14.     
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TitleCellular Signaling in Health and Disease
Author(s)Beckerman, Martin
PublicationNew York, NY, 1. Imprint: Springer 2. Springer New York, 2009.
DescriptionXVIII, 470 p. 193 illus : online resource
Abstract NoteIn today???s world, three great classes of non-infectious diseases ??? the metabolic syndromes (such as type 2 diabetes and atherosclerosis), the cancers, and the neurodegenerative disorders ??? have risen to the fore. These diseases, all associated with increasing age of an individual, have proven to be remarkably complex and difficult to treat. This is because, in large measure, when the cellular signaling pathways responsible for maintaining homeostasis and health of the body become dysregulated, they generate equally stable disease states. As a result the body may respond positively to a drug, but only for a while and then revert back to the disease state. Cellular Signaling in Health and Disease summarizes our current understanding of these regulatory networks in the healthy and diseased states, showing which molecular components might be prime targets for drug interventions. This is accomplished by presenting models that explain in mechanistic, molecular detail how a particular part of the cellular signaling web operates properly in health and improperly in disease. The stability of the health- and disease-associated states is dynamic and supported by multiple feedback loops acting positively and negatively along with linkages between pathways. During the past few years an ongoing series of important discoveries have been made that advance our understanding of how the body works and may guide us on how to better deal with these diseases. These include the discovery of chronic inflammation as a causal factor in all of these disease classes, the appearance of reactive oxygen species as a messenger molecule that can act both positively and negatively, the propensity of proteins to misfold into aggregation- and disease-prone forms, and the rise of epigenetics including the emergence of small non-coding RNA with important regulatory functions out of the so-called junk RNA. Chapters are devoted to each of these classes of findings with additional details integrated into the chapters dealing directly with the diseases. The connections responsible for maintaining stability are explored in depth
ISBN,Price9780387981734
Keyword(s)1. BIOCHEMISTRY 2. Biochemistry, general 3. Biological and Medical Physics, Biophysics 4. BIOLOGICAL PHYSICS 5. Biomedical engineering 6. Biomedical Engineering and Bioengineering 7. BIOPHYSICS 8. CELL BIOLOGY 9. EBOOK 10. EBOOK - SPRINGER 11. Human physiology 12. MOLECULAR BIOLOGY 13. Molecular Medicine
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15.     
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TitleBiophysics of DNA-Protein Interactions : From Single Molecules to Biological Systems
Author(s)Williams, Mark C;Maher, III, L. James
PublicationNew York, NY, 1. Imprint: Springer 2. Springer New York, 2011.
DescriptionX, 350 p : online resource
Abstract NoteThis book presents a concise overview of current research on the biophysics of DNA-protein interactions. A wide range of new and classical methods are presented by authors investigating physical mechanisms by which proteins interact with DNA. For example, several chapters address the mechanisms by which proteins search for and recognize specific binding sites on DNA, a process critical for cellular function. Single molecule methods such as force spectroscopy as well as fluorescence imaging and tracking are described in these chapters as well as other parts of the book that address the dynamics of protein-DNA interactions. Other important topics include the mechanisms by which proteins engage DNA sequences and/or alter DNA structure. These simple but important model interactions are then placed in the broader biological context with discussion of larger protein-DNA complexes . Topics include replication forks, recombination complexes, DNA repair interactions, and ultimately, methods to understand the chromatin context of the cell nucleus. This book will be of interest to readers who wish to explore current biophysical approaches to DNA-protein interactions across multiple levels of biological complexity
ISBN,Price9780387928081
Keyword(s)1. BIOCHEMISTRY 2. Biochemistry, general 3. Biological and Medical Physics, Biophysics 4. BIOLOGICAL PHYSICS 5. Biomedical engineering 6. Biomedical Engineering and Bioengineering 7. BIOPHYSICS 8. CELL BIOLOGY 9. EBOOK 10. EBOOK - SPRINGER 11. MOLECULAR BIOLOGY 12. Molecular Medicine 13. Protein Structure 14. Proteins??
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16.     
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TitleOxygen Transport to Tissue XXVII
Author(s)Cicco, Giuseppe;Bruley, Duane F;Ferrari, Marc
PublicationNew York, NY, 1. Imprint: Springer 2. Springer US, 2006.
DescriptionXXV, 390 p : online resource
Abstract NoteProceedings of the 32nd scientific meeting of the International Society on Oxygen Transport to Tissue (ISOTT) in Bari, Italy, August 21-26, 2004
ISBN,Price9780387295404
Keyword(s)1. ANATOMY 2. BIOCHEMISTRY 3. Biochemistry, general 4. Biological and Medical Physics, Biophysics 5. BIOLOGICAL PHYSICS 6. BIOPHYSICS 7. CELL BIOLOGY 8. EBOOK 9. EBOOK - SPRINGER 10. Human anatomy
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17.     
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TitleThe Thermodynamic Machinery of Life
Author(s)Kurzynski, Michal
PublicationBerlin, Heidelberg, 1. Imprint: Springer 2. Springer Berlin Heidelberg, 2006.
DescriptionXIV, 431 p. 150 illus : online resource
Abstract NoteLiving organisms are open thermodynamic systems whose functional structure has developed and been kinetically frozen during the historical process of biological evolution. A thermodynamics of both nonequilibrium and complex systems is needed for their description. In this book, the foundations of such a thermodynamics are presented. Biological processes at the cellular level are considered as coupled chemical reactions and transport processes across internal and the cytoplasmic membrane. All these processes are catalyzed by specific enzymes hence the kinetics of enzymatic catalysis and its control are described here in detail. The coupling of several processes through a common enzyme is considered in the context of free energy or signal transduction. Special attention is paid to evidence for a rich stochastic internal dynamics of native proteins and its possible role in the control of enzyme activity and in the action of biological molecular machines
ISBN,Price9783540336549
Keyword(s)1. BIOCHEMISTRY 2. Biochemistry, general 3. Biological and Medical Physics, Biophysics 4. BIOLOGICAL PHYSICS 5. BIOPHYSICS 6. CELL BIOLOGY 7. EBOOK 8. EBOOK - SPRINGER 9. ORGANIC CHEMISTRY 10. THERMODYNAMICS
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18.     
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TitleProtein-Lipid Interactions : New Approaches and Emerging Concepts
Author(s)Mateo, C.Reyes;G??mez, Javier;Villala??n, Jos??;Gonz??lez Ros, Jos?? Manuel
PublicationBerlin, Heidelberg, 1. Imprint: Springer 2. Springer Berlin Heidelberg, 2006.
DescriptionXIV, 235 p : online resource
Abstract NoteBiological membranes have long been identified as key elements in a wide variety of cellular processes including cell defense communication, photosynthesis, signal transduction, and motility; thus they emerge as primary targets in both basic and applied research. This book brings together in a single volume the most recent views of experts in the area of protein???lipid interactions, providing an overview of the advances that have been achieved in the field in recent years, from very basic aspects to specialized technological applications. Topics include the application of X-ray and neutron diffraction, infrared and fluorescence spectroscopy, and high-resolution NMR to the understanding of the specific interactions between lipids and proteins within biological membranes, their structural relationships, and the implications for the biological functions that they mediate. Also covered in this volume are the insertion of proteins and peptides into the membrane and the concomitant formation of definite lipid domains within the membrane
ISBN,Price9783540284352
Keyword(s)1. BIOCHEMISTRY 2. Biochemistry, general 3. Biological and Medical Physics, Biophysics 4. BIOLOGICAL PHYSICS 5. Bioorganic Chemistry 6. BIOPHYSICS 7. CELL BIOLOGY 8. EBOOK 9. EBOOK - SPRINGER
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19.     
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TitleSensing with Ion Channels
Author(s)Martinac, Boris
PublicationBerlin, Heidelberg, 1. Imprint: Springer 2. Springer Berlin Heidelberg, 2008.
DescriptionXXIII, 304 p : online resource
Abstract NoteAll living cells are able to detect and translate environmental stimuli into biologically meaningful signals. Sensations of touch, hearing, sight, taste, smell or pain are essential to the survival of all living organisms. The importance of sensory input for the existence of life thus justifies the effort made to understand its molecular origins. Sensing with Ion Channels focuses on ion channels as key molecules enabling biological systems to sense and process the physical and chemical stimuli that act upon cells in their living environment. Its aim is to serve as a reference to ion channel specialists and as a source of new information to non specialists who want to learn about the structural and functional diversity of ion channels and their role in sensory physiology
ISBN,Price9783540727392
Keyword(s)1. BIOCHEMISTRY 2. Biochemistry, general 3. Biological and Medical Physics, Biophysics 4. BIOLOGICAL PHYSICS 5. Bioorganic Chemistry 6. BIOPHYSICS 7. CELL BIOLOGY 8. EBOOK 9. EBOOK - SPRINGER
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20.    
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TitleStochastic Narrow Escape in Molecular and Cellular Biology : Analysis and Applications
Author(s)Holcman, David;Schuss, Zeev
PublicationNew York, NY, 1. Imprint: Springer 2. Springer New York, 2015.
DescriptionXIX, 259 p. 76 illus., 38 illus. in color : online resource
Abstract NoteThis book covers recent developments in the non-standard asymptotics of the mathematical narrow escape problem in stochastic theory, as well as applications of the narrow escape problem in cell biology. The first part of the book concentrates on mathematical methods, including advanced asymptotic methods in partial equations, and is aimed primarily at applied mathematicians and theoretical physicists who are interested in biological applications. The second part of the book is intended for computational biologists, theoretical chemists, biochemists, biophysicists, and physiologists. It includes a summary of output formulas from the mathematical portion of the book and concentrates on their applications in modeling specific problems in theoretical molecular and cellular biology. Critical biological processes, such as synaptic plasticity and transmission, activation of genes by transcription factors, or double-strained DNA break repair, are controlled by diffusion in structures that have both large and small spatial scales. These may be small binding sites inside or on the surface of the cell, or narrow passages between subcellular compartments. The great disparity in spatial scales is the key to controlling cell function by structure. This volume reports recent progress on resolving analytical and numerical difficulties in extracting properties from experimental data, biophysical models, and from Brownian dynamics simulations of diffusion in multi-scale structures
ISBN,Price9781493931033
Keyword(s)1. Biological and Medical Physics, Biophysics 2. BIOLOGICAL PHYSICS 3. BIOMATHEMATICS 4. BIOPHYSICS 5. CELL BIOLOGY 6. EBOOK 7. EBOOK - SPRINGER 8. Mathematical and Computational Biology 9. Numerical and Computational Physics, Simulation 10. PHYSICS
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