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 #  AuthorTitleAccn#YearItem Type Claims
11 Zhegunov, Gennadiy The Dual Nature of Life I08330 2012 eBook  
12 Bloomfield, Victor Computer Simulation and Data Analysis in Molecular Biology and Biophysics I07851 2009 eBook  
13 Damjanovich, Sandor Biophysical Aspects of Transmembrane Signaling I07832 2005 eBook  
14 Walter, Nils Non-Protein Coding RNAs I07807 2009 eBook  
15 Glaser, Roland Biophysics I07449 2012 eBook  
16 Skulachev, Vladimir P Principles of Bioenergetics I07211 2013 eBook  
17 Beckerman, Martin Cellular Signaling in Health and Disease I06893 2009 eBook  
18 Williams, Mark C Biophysics of DNA-Protein Interactions I06889 2011 eBook  
19 Cicco, Giuseppe Oxygen Transport to Tissue XXVII I06737 2006 eBook  
20 Kurzynski, Michal The Thermodynamic Machinery of Life I06609 2006 eBook  
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11.    
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TitleThe Dual Nature of Life : Interplay of the Individual and the Genome
Author(s)Zhegunov, Gennadiy
PublicationBerlin, Heidelberg, Springer Berlin Heidelberg, 2012.
DescriptionXII, 300 p : online resource
Abstract NoteLife is a diverse and ubiquitous phenomenon on Earth, characterized by fundamental features distinguishing living bodies from nonliving material. Yet it is also so complex that it has long defied precise definition. This book from a seasoned biologist offers new insights into the nature of life by illuminating a fascinating architecture of dualities inherent in its existence and propagation. Life is connected with individual living beings, yet it is also a collective and inherently global phenomenon of the material world. It embodies a dual existence of cycles of phenotypic life, and their unseen driver ??? an uninterrupted march of genetic information whose collective immortality is guaranteed by individual mortality. Although evolution propagates and tunes species of organisms, the beings produced can be regarded merely as tools for the survival and cloning of genomes written in an unchanging code. What are the physical versus informational bases and driving forces of life, and how do they unite as an integrated system? What does time mean for individuals, life on the global scale, and the underlying information? This accessible examination of principles and evidence shows that a network of dualities lies at the heart of biological puzzles that have engaged the human mind for millennia
ISBN,Price9783642303944
Keyword(s)1. CELL BIOLOGY 2. EBOOK 3. EBOOK - SPRINGER 4. Evolutionary Biology 5. Popular Science, general 6. Popular works
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12.     
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TitleComputer Simulation and Data Analysis in Molecular Biology and Biophysics : An Introduction Using R
Author(s)Bloomfield, Victor
PublicationNew York, NY, Springer New York, 2009.
DescriptionXVI, 321 p : online resource
Abstract NoteThis book provides an introduction, suitable for advanced undergraduates and beginning graduate students, to two important aspects of molecular biology and biophysics: computer simulation and data analysis. It introduces tools to enable readers to learn and use fundamental methods for constructing quantitative models of biological mechanisms, both deterministic and with some elements of randomness, including complex reaction equilibria and kinetics, population models, and regulation of metabolism and development; to understand how concepts of probability can help in explaining important features of DNA sequences; and to apply a useful set of statistical methods to analysis of experimental data from spectroscopic, genomic, and proteomic sources. These quantitative tools are implemented using the free, open source software program R. R provides an excellent environment for general numerical and statistical computing and graphics, with capabilities similar to Matlab??. Since R is increasingly used in bioinformatics applications such as the BioConductor project, it can serve students as their basic quantitative, statistical, and graphics tool as they develop their careers
ISBN,Price9781441900838
Keyword(s)1. BIOCHEMISTRY 2. Biochemistry, general 3. Bioinformatics?? 4. Biological and Medical Physics, Biophysics 5. BIOLOGICAL PHYSICS 6. Biomedical engineering 7. Biomedical Engineering and Bioengineering 8. BIOPHYSICS 9. CELL BIOLOGY 10. Computational biology?? 11. Computer Appl. in Life Sciences 12. EBOOK 13. EBOOK - SPRINGER 14. Science, Humanities and Social Sciences, multidisciplinary
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13.     
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TitleBiophysical Aspects of Transmembrane Signaling
Author(s)Damjanovich, Sandor
PublicationBerlin, Heidelberg, Springer Berlin Heidelberg, 2005.
DescriptionXVIII, 322 p. 41 illus., 18 illus. in color : online resource
Abstract NoteTransmembrane signaling is one of the most significant cell biological events in the life and death of cells in general and lymphocytes in particular. Until recently biochemists and biophysicists were not accustomed to thinking of these processes from the side of a high number of complex biochemical events and an equally high number of physical changes at molecular and cellular levels at the same time. Both types of researchers were convinced that their findings are the most decisive, having higher importance than the findings of the other scientist population. Both casts were wrong. Life, even at cellular level, has a number of interacting physical and biochemical mechanisms, which finally build up the creation of an "excited" cell that will respond to particular signals from the outer or inner world. This book handles both aspects of the signalling events, and in some cases tries to unify our concepts and help understand the signals that govern the life and death of our cells. Not only the understanding, but also the interference (e.g. medication) may depend on the full knowledge of both sides. These above statements are supported by the application of highly diverse physical and biochemical technologies demonstrated and explained by experts who are pioneers of their particular scientific field
ISBN,Price9783540265115
Keyword(s)1. BIOCHEMISTRY 2. Biochemistry, general 3. Biological and Medical Physics, Biophysics 4. BIOLOGICAL PHYSICS 5. BIOPHYSICS 6. CELL BIOLOGY 7. EBOOK 8. EBOOK - SPRINGER
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14.     
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TitleNon-Protein Coding RNAs
Author(s)Walter, Nils;Woodson, Sarah A;Batey, Robert T
PublicationBerlin, Heidelberg, Springer Berlin Heidelberg, 2009.
DescriptionXI, 398 p : online resource
Abstract NoteThis book assembles chapters from experts in the Biophysics of RNA to provide a broadly accessible snapshot of the current status of this rapidly expanding field. The 2006 Nobel Prize in Physiology or Medicine was awarded to the discoverers of RNA interference, highlighting just one example of a large number of non-protein coding RNAs. Because non-protein coding RNAs outnumber protein coding genes in mammals and other higher eukaryotes, it is now thought that the complexity of organisms is correlated with the fraction of their genome that encodes non-protein coding RNAs. Essential biological processes as diverse as cell differentiation, suppression of infecting viruses and parasitic transposons, higher-level organization of eukaryotic chromosomes, and gene expression itself are found to largely be directed by non-protein coding RNAs. The biophysical study of these RNAs employs X-ray crystallography, NMR, ensemble and single molecule fluorescence spectroscopy, optical tweezers, cryo-electron microscopy, and other quantitative tools. This emerging field has begun to unravel the molecular underpinnings of how RNAs fulfill their multitude of roles in sustaining cellular life. The physical and chemical understanding of RNA biology that results from biophysical studies is critical to our ability to harness RNAs for use in biotechnology and human therapy, a prospect that has recently spawned a multi-billion dollar industry
ISBN,Price9783540708407
Keyword(s)1. BIOCHEMISTRY 2. Biochemistry, general 3. BIOINFORMATICS 4. Biological and Medical Physics, Biophysics 5. BIOLOGICAL PHYSICS 6. BIOPHYSICS 7. CELL BIOLOGY 8. EBOOK 9. EBOOK - SPRINGER 10. Human physiology 11. MOLECULAR BIOLOGY 12. Molecular Medicine
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15.     
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TitleBiophysics : An Introduction
Author(s)Glaser, Roland
PublicationBerlin, Heidelberg, Springer Berlin Heidelberg, 2012.
DescriptionXX, 407 p. 188 illus., 134 illus. in color : online resource
Abstract NoteBiophysics is the science of physical principles underlying all processes of life, including the dynamics and kinetics of biological systems. This fully revised 2nd English edition is an introductory text that spans all steps of biological organization, from the molecular, to the organism level, as well as influences of environmental factors. In response to the enormous progress recently made, especially in theoretical and molecular biophysics, the author has updated the text, integrating new results and developments concerning protein folding and dynamics, molecular aspects of membrane assembly and transport, noise-enhanced processes, and photo-biophysics. The advances made in theoretical biology in the last decade call for a fully new conception of the corresponding sections. Thus, the book provides the background needed for fundamental training in biophysics and, in addition, offers a great deal of advanced biophysical knowledge
ISBN,Price9783642252129
Keyword(s)1. BIOCHEMISTRY 2. Biochemistry, general 3. Biological and Medical Physics, Biophysics 4. BIOLOGICAL PHYSICS 5. BIOPHYSICS 6. CELL BIOLOGY 7. EBOOK 8. EBOOK - SPRINGER 9. Effects of Radiation/Radiation Protection 10. Human physiology 11. Radiation protection 12. Radiation???Safety measures
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16.     
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TitlePrinciples of Bioenergetics
Author(s)Skulachev, Vladimir P;Bogachev, Alexander V;Kasparinsky, Felix O
PublicationBerlin, Heidelberg, Springer Berlin Heidelberg, 2013.
DescriptionXVI, 436 p : online resource
Abstract NotePrinciples of Bioenergetics summarizes one of the quickly growing branches of modern biochemistry.??Bioenergetics concerns energy transductions occurring in living systems and??this book pays special attention to molecular mechanisms of these processes.??The main subject of the book is the "energy coupling membrane" which refers to??inner membranes of intracellular organelles, for example, mitochondria and chloroplasts. Cellular cytoplasmic membranes where respiratory and photosynthetic energy transducers, as well as ion-transporting ATP-synthases (ATPases)??are also part of this membrane.??Significant attention is paid to the alternative function of mitochondria as generators of reactive oxygen species (ROS) that mediate programmed death of cells (apoptosis and necrosis) and organisms (phenoptosis). The latter process is considered as a key mechanism of aging which may be suppressed by mitochondria-targeted antioxidants
ISBN,Price9783642334306
Keyword(s)1. Biological and Medical Physics, Biophysics 2. BIOLOGICAL PHYSICS 3. BIOPHYSICS 4. CELL BIOLOGY 5. EBOOK 6. EBOOK - SPRINGER 7. Geriatrics 8. Geriatrics/Gerontology 9. Medicinal chemistry 10. PHYSICAL CHEMISTRY
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17.     
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TitleCellular Signaling in Health and Disease
Author(s)Beckerman, Martin
PublicationNew York, NY, Springer New York, 2009.
DescriptionXVIII, 470 p. 193 illus : online resource
Abstract NoteIn today???s world, three great classes of non-infectious diseases ??? the metabolic syndromes (such as type 2 diabetes and atherosclerosis), the cancers, and the neurodegenerative disorders ??? have risen to the fore. These diseases, all associated with increasing age of an individual, have proven to be remarkably complex and difficult to treat. This is because, in large measure, when the cellular signaling pathways responsible for maintaining homeostasis and health of the body become dysregulated, they generate equally stable disease states. As a result the body may respond positively to a drug, but only for a while and then revert back to the disease state. Cellular Signaling in Health and Disease summarizes our current understanding of these regulatory networks in the healthy and diseased states, showing which molecular components might be prime targets for drug interventions. This is accomplished by presenting models that explain in mechanistic, molecular detail how a particular part of the cellular signaling web operates properly in health and improperly in disease. The stability of the health- and disease-associated states is dynamic and supported by multiple feedback loops acting positively and negatively along with linkages between pathways. During the past few years an ongoing series of important discoveries have been made that advance our understanding of how the body works and may guide us on how to better deal with these diseases. These include the discovery of chronic inflammation as a causal factor in all of these disease classes, the appearance of reactive oxygen species as a messenger molecule that can act both positively and negatively, the propensity of proteins to misfold into aggregation- and disease-prone forms, and the rise of epigenetics including the emergence of small non-coding RNA with important regulatory functions out of the so-called junk RNA. Chapters are devoted to each of these classes of findings with additional details integrated into the chapters dealing directly with the diseases. The connections responsible for maintaining stability are explored in depth
ISBN,Price9780387981734
Keyword(s)1. BIOCHEMISTRY 2. Biochemistry, general 3. Biological and Medical Physics, Biophysics 4. BIOLOGICAL PHYSICS 5. Biomedical engineering 6. Biomedical Engineering and Bioengineering 7. BIOPHYSICS 8. CELL BIOLOGY 9. EBOOK 10. EBOOK - SPRINGER 11. Human physiology 12. MOLECULAR BIOLOGY 13. Molecular Medicine
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18.     
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TitleBiophysics of DNA-Protein Interactions : From Single Molecules to Biological Systems
Author(s)Williams, Mark C;Maher, III, L. James
PublicationNew York, NY, Springer New York, 2011.
DescriptionX, 350 p : online resource
Abstract NoteThis book presents a concise overview of current research on the biophysics of DNA-protein interactions. A wide range of new and classical methods are presented by authors investigating physical mechanisms by which proteins interact with DNA. For example, several chapters address the mechanisms by which proteins search for and recognize specific binding sites on DNA, a process critical for cellular function. Single molecule methods such as force spectroscopy as well as fluorescence imaging and tracking are described in these chapters as well as other parts of the book that address the dynamics of protein-DNA interactions. Other important topics include the mechanisms by which proteins engage DNA sequences and/or alter DNA structure. These simple but important model interactions are then placed in the broader biological context with discussion of larger protein-DNA complexes . Topics include replication forks, recombination complexes, DNA repair interactions, and ultimately, methods to understand the chromatin context of the cell nucleus. This book will be of interest to readers who wish to explore current biophysical approaches to DNA-protein interactions across multiple levels of biological complexity
ISBN,Price9780387928081
Keyword(s)1. BIOCHEMISTRY 2. Biochemistry, general 3. Biological and Medical Physics, Biophysics 4. BIOLOGICAL PHYSICS 5. Biomedical engineering 6. Biomedical Engineering and Bioengineering 7. BIOPHYSICS 8. CELL BIOLOGY 9. EBOOK 10. EBOOK - SPRINGER 11. MOLECULAR BIOLOGY 12. Molecular Medicine 13. Protein Structure 14. Proteins??
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19.     
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TitleOxygen Transport to Tissue XXVII
Author(s)Cicco, Giuseppe;Bruley, Duane F;Ferrari, Marc
PublicationNew York, NY, Springer US, 2006.
DescriptionXXV, 390 p : online resource
Abstract NoteProceedings of the 32nd scientific meeting of the International Society on Oxygen Transport to Tissue (ISOTT) in Bari, Italy, August 21-26, 2004
ISBN,Price9780387295404
Keyword(s)1. ANATOMY 2. BIOCHEMISTRY 3. Biochemistry, general 4. Biological and Medical Physics, Biophysics 5. BIOLOGICAL PHYSICS 6. BIOPHYSICS 7. CELL BIOLOGY 8. EBOOK 9. EBOOK - SPRINGER 10. Human anatomy
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20.    
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TitleThe Thermodynamic Machinery of Life
Author(s)Kurzynski, Michal
PublicationBerlin, Heidelberg, Springer Berlin Heidelberg, 2006.
DescriptionXIV, 431 p. 150 illus : online resource
Abstract NoteLiving organisms are open thermodynamic systems whose functional structure has developed and been kinetically frozen during the historical process of biological evolution. A thermodynamics of both nonequilibrium and complex systems is needed for their description. In this book, the foundations of such a thermodynamics are presented. Biological processes at the cellular level are considered as coupled chemical reactions and transport processes across internal and the cytoplasmic membrane. All these processes are catalyzed by specific enzymes hence the kinetics of enzymatic catalysis and its control are described here in detail. The coupling of several processes through a common enzyme is considered in the context of free energy or signal transduction. Special attention is paid to evidence for a rich stochastic internal dynamics of native proteins and its possible role in the control of enzyme activity and in the action of biological molecular machines
ISBN,Price9783540336549
Keyword(s)1. BIOCHEMISTRY 2. Biochemistry, general 3. Biological and Medical Physics, Biophysics 4. BIOLOGICAL PHYSICS 5. BIOPHYSICS 6. CELL BIOLOGY 7. EBOOK 8. EBOOK - SPRINGER 9. ORGANIC CHEMISTRY 10. THERMODYNAMICS
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